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Fitment on a used radio varies by vehicle, so a bit of detail goes a long way. Our request form covers what breakers need to know, so every quote you get back is for the correct part:
The SLK ran across three generations: R170 (1996–2004), R171 (2004–2011), and R172 (2011–2016), and radios are generally generation-specific due to differences in the dashboard fascia, wiring looms, and control interfaces between each generation. Within the same generation you'll have the best chance of a straight swap, though software and coding requirements can still vary by build year. Always confirm the exact part number and generation with the breaker against your registration before buying.
Both a 2006 and a 2009 SLK fall within the R171 generation (2004–2011), so the physical fitment and wiring are likely to be compatible. That said, radios within the R171 can differ in specification depending on optional equipment fitted new, so ask the breaker to match the part number or at least confirm the head unit type against your registration. This is particularly worth checking if one car has sat-nav and the other doesn't, as the units are different.
The R170 and R171 are distinct generations with different dashboard designs and wiring architecture, so a radio from the R170 is very unlikely to drop straight into an R171 without significant modification. This is a known generation boundary where interchangeability is not reliable, and we'd route this firmly to the breaker to confirm whether any adaptation is possible before you commit to buying. Sticking to a radio sourced from the same generation is strongly recommended.
Trim level doesn't fundamentally change the radio fitment in the way that generation or build year does, so a unit from a standard SLK and one from a higher-spec trim within the same generation will typically share the same physical fitting and connector. However, higher-spec or AMG-badged cars were more likely to be ordered with Comand navigation or premium audio systems, which are different head units to the standard radio, so you may notice a difference in the unit's features or finish. Ask the breaker to confirm the specific head unit type fitted to their donor car matches what you need, rather than relying on trim name alone.
Mercedes-Benz did share some head unit hardware across models of the same era, so it's not impossible for a unit from a contemporary C-Class or E-Class to be physically similar, but fascia sizes, wiring plugs, and software coding often differ between model lines. We wouldn't assume compatibility without checking, and this is something to put directly to the breaker, who can compare part numbers across their stock. Don't buy on model similarity alone — always confirm against your registration.
Both years sit within the R172 generation (2011–2016), so the fundamental fitment should be the same and a swap within this generation is a reasonable starting point. Minor updates to software or unit specification can occur across a model's life even without a formal facelift, so it's worth asking the breaker to confirm the part number matches or is a known compatible alternative. Never guarantee fitment based on generation alone — always verify with the breaker using your registration.