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No two throttle bodys are quite the same across different vehicles, so getting the specifics right matters when you buy used, second hand or a replacement. Answer a few quick questions below and breakers will only quote if they have the exact matching part in stock:
It depends entirely on the engine variant. The petrol-engined 159s — including the 1.8, 2.0, 2.2 JTS and 3.2 V6 — do have a throttle body controlling airflow into the engine. The diesel variants (1.9 JTDM, 2.4 JTDM) are common-rail diesel engines and do not use a traditional throttle body in the same way, so if you have a diesel 159 this is almost certainly not the part you need — you may be looking for a swirl flap assembly or EGR valve instead.
The Alfa Romeo 159 was produced as a single generation running from 2005 to 2011, with a facelift arriving around 2008, so a 2005 and a 2010 car do span that facelift boundary. The engine code is the key detail here — a throttle body is matched to the specific engine, not the model year, so if both cars share the same engine code (found on your V5 or via a VIN check) there is a strong chance of compatibility, but whether any ancillary or mounting changes were introduced at the 2008 facelift is something you should confirm with the breaker against your exact registration before buying.
Trim level makes no difference whatsoever to throttle body fitment on the 159 — Lusso, Ti, and Veloce are specification packages affecting interior, equipment, and cosmetics, not the engine hardware. What matters is your engine code, which will be the same across all trims fitted with the same engine. Give the breaker your engine code and registration rather than your trim name and you will get a much more useful answer.
The 2.2 JTS and the 1.8 are different engines with different engine codes, and a throttle body is sized and calibrated for a specific engine, so they are very unlikely to be interchangeable. Always quote your exact engine code (visible on your V5C or confirmed via a VIN check) to the breaker rather than just the displacement, as this is the single most reliable way to ensure you are quoted the correct unit.
This is a question that genuinely varies depending on the specific engine management system fitted to your car, and it is not something that can be answered with certainty here. Some throttle bodies require adaptation or calibration via a diagnostic tool after fitting, and there may also be ECU pairing considerations on certain variants — confirm this with the breaker and ideally with a specialist or Alfa Romeo dealer before purchasing a used unit so you are not caught out by unexpected coding costs.
Be cautious — the engine code is the definitive guide for throttle body fitment, and different engine sizes almost always mean different engine codes and different throttle body specifications. A breaker who is confident of a cross-application should be able to tell you the specific engine codes of both the donor and your vehicle and explain why they are compatible; if they cannot, it is safer to find a unit pulled from a car with a matching engine code to yours.