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A used ac compressor that fits one vehicle won't always fit another - even within the same model range. These questions help breakers match stock to your exact vehicle before they quote:
These are different generations: the W221 ran from 2005 to 2013, and the W222 started in 2013, so a 2010 unit is from the outgoing generation and a 2014 unit is from the new one. Across that generational boundary the compressor design changed, and fitment cannot be assumed. Always confirm with the breaker against your exact registration and engine code before buying.
The W221 S-Class ran from 2005 to 2013, with a facelift introduced in 2009, and both sit within the same generation. Whether the compressor crosses that 2009 facelift boundary cleanly depends on your exact engine code, as ancillary and mounting details can change mid-production even within a generation. Give the breaker your registration and engine code so they can match against a like-for-like unit.
Trim level and badge don't affect AC compressor fitment on the S-Class; what matters is the engine code, fuel type, and gearbox type. An S350 and an S500 run entirely different engines, so their compressors are not interchangeable simply because they share the same generation and body. Always match on engine code rather than model badge, and confirm with the breaker against your registration.
The W222 ran from 2013 to 2020, with a facelift in 2017, and covers a wide spread of petrol and diesel engines across those years. Engine code is the single most reliable guide here, sitting above year or fuel type alone — pull yours from the V5 or a VIN check before approaching a breaker. Confirm the match against your registration with the breaker, as ancillary and mounting details can vary within the same generation.
Fuel type is a key fitment factor for AC compressors, and a diesel unit will not reliably swap onto a petrol engine even if the cars are the same year and generation. The engine code is the definitive guide and will tell you and the breaker exactly what compressor is correct for your car. Check your engine code on the V5 or via a VIN check and quote it to the breaker when requesting a part.
Whether an AC compressor requires ECU pairing or any immobiliser coding on your specific S-Class is something we can't state as fact here, as this can vary and is best confirmed directly with the breaker against your registration. What is straightforward is that the mechanical match must come first — engine code, fuel type, and gearbox type all need to align before any electrical considerations. Ask the breaker explicitly about coding requirements when you get your quote.